The striatin family: a new signaling platform in dendritic spines

Marion Benoist; Stéphane Gaillard; Francis Castets

doi:10.1016/j.jphysparis.2005.12.006

The striatin family: a new signaling platform in dendritic spines

J Physiol Paris. 2006 Mar-May;99(2-3):146-53. doi: 10.1016/j.jphysparis.2005.12.006. Epub 2006 Feb 7.

Authors

Marion Benoist¹, Stéphane Gaillard, Francis Castets

Affiliation

¹ INSERM-UMR 641, Institut Jean Roche, Université de la Méditerranée, Faculté de Médecine Secteur-Nord, Boulevard P. Dramard, 13916 Marseille cedex 20, France.

PMID: 16460920
DOI: 10.1016/j.jphysparis.2005.12.006

Abstract

Proteins of the striatin family have been identified in all multicellular animals. They are multidomain molecules containing several protein-interacting motifs. In mammals, these proteins are principally expressed in neurons with a somato-dendritic localization and high concentration in dendritic spines. Recent reports suggest that the proteins of the striatin family are molecular scaffolds that act as links between signal transduction and vesicular trafficking.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Calmodulin-Binding Proteins / chemistry
Calmodulin-Binding Proteins / classification*
Calmodulin-Binding Proteins / physiology*
Dendritic Spines / metabolism*
Humans
Models, Biological
Molecular Structure
Protein Structure, Tertiary / physiology
Signal Transduction / physiology*

Substances

Calmodulin-Binding Proteins