Hydrogen production and deuterium-proton exchange reactions catalyzed by Desulfovibrio nickel(II)-substituted rubredoxins

P Saint-Martin; P A Lespinat; G Fauque; Y Berlier; J Legall; I Moura; M Teixeira; A V Xavier; J J Moura

doi:10.1073/pnas.85.24.9378

Hydrogen production and deuterium-proton exchange reactions catalyzed by Desulfovibrio nickel(II)-substituted rubredoxins

Proc Natl Acad Sci U S A. 1988 Dec;85(24):9378-80. doi: 10.1073/pnas.85.24.9378.

Authors

P Saint-Martin¹, P A Lespinat, G Fauque, Y Berlier, J Legall, I Moura, M Teixeira, A V Xavier, J J Moura

Affiliation

¹ L'Association pour la Recherche en Bioenergie Solaire, Section Enzymologie et Biochimie Bactérienne, Centre d'Etudes Nucleaires, Cadarache, 13108 Saint-Paul-lez-Durance Cedex, France.

Abstract

The nickel tetrahedral sulfur-coordinated core formed upon metal replacement of the native iron in Desulfovibrio sp. rubredoxins is shown to mimic the reactivity pattern of nickel-containing hydrogenases with respect to hydrogen production, deuterium-proton exchange, and inhibition by carbon monoxide.