Abstract
Ciprofloxacin-resistant Escherichia coli isolates (n = 1,858) from outpatient midstream urine specimens at 40 North American clinical laboratories in 2004 to 2005 were frequently resistant to ampicillin (79.8% of isolates) and trimethoprim-sulfamethoxazole (66.5%); concurrent resistance to cefdinir (9.0%) or nitrofurantoin (4.0%) was less common. Only 10.8% of isolates were resistant to ciprofloxacin alone. Fluoroquinolone-resistant isolates of E. coli from urine were frequently multidrug resistant.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Ampicillin / therapeutic use
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Anti-Infective Agents, Urinary / therapeutic use*
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Cefdinir
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Cephalosporins / therapeutic use
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Ciprofloxacin / therapeutic use
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Drug Resistance, Bacterial
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Drug Resistance, Multiple, Bacterial / genetics*
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Escherichia coli / drug effects*
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Escherichia coli / genetics
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Escherichia coli / isolation & purification
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Escherichia coli Infections / drug therapy
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Escherichia coli Infections / microbiology
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Female
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Fluoroquinolones / therapeutic use*
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Humans
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In Vitro Techniques
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Nitrofurantoin / therapeutic use
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North America
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Outpatients
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Trimethoprim, Sulfamethoxazole Drug Combination
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Urinary Tract Infections / drug therapy*
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Urinary Tract Infections / microbiology
Substances
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Anti-Infective Agents, Urinary
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Cephalosporins
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Fluoroquinolones
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Ciprofloxacin
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Ampicillin
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Trimethoprim, Sulfamethoxazole Drug Combination
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Nitrofurantoin
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Cefdinir