Abstract
The CR1 element defined by an orf513 gene encoding a putative recombinase and a recombination crossover site has been identified upstream of several antibiotic resistance genes in Enterobacteriaceae. This CR1 element was shown to bring promoter sequences that play a role in the expression of unrelated antibiotic resistance genes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism*
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Base Sequence
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Drug Resistance, Bacterial / genetics*
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Enterobacteriaceae / drug effects
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Enterobacteriaceae / genetics*
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Enterobacteriaceae / metabolism
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Gene Expression Regulation, Bacterial*
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Humans
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Integrons / genetics*
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Molecular Sequence Data
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Promoter Regions, Genetic
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Recombinases / genetics*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Recombinases