Abstract
A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Biological Assay*
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Bone Marrow Cells* / drug effects
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Bone Marrow Cells* / immunology
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Cell Adhesion
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Cells, Immobilized
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Dendritic Cells* / drug effects
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Dendritic Cells* / immunology
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Female
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Male
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Mice
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Mice, Inbred C57BL
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Phagocytosis*
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Polyurethanes / chemical synthesis
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Polyurethanes / chemistry*
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Polyurethanes / pharmacology