Enantioselective reduction of ketones with "designer cells" at high substrate concentrations: highly efficient access to functionalized optically active alcohols

Angew Chem Int Ed Engl. 2006 Aug 25;45(34):5677-81. doi: 10.1002/anie.200503394.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohol Dehydrogenase / chemistry*
  • Alcohol Dehydrogenase / genetics
  • Alcohols* / chemical synthesis
  • Alcohols* / chemistry
  • Catalysis
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli / growth & development
  • Glucose 1-Dehydrogenase / chemistry*
  • Glucose 1-Dehydrogenase / genetics
  • Ketones / chemistry*
  • Molecular Structure
  • Oxidation-Reduction
  • Stereoisomerism
  • Substrate Specificity

Substances

  • Alcohols
  • Ketones
  • Alcohol Dehydrogenase
  • Glucose 1-Dehydrogenase