Hexaprenoid hydroquinones from the sponge Haliclona (aka Adocia) sp

Lyndon M West; D John Faulkner

doi:10.1021/np050459c

Hexaprenoid hydroquinones from the sponge Haliclona (aka Adocia) sp

J Nat Prod. 2006 Jul;69(7):1001-4. doi: 10.1021/np050459c.

Authors

Lyndon M West¹, D John Faulkner

Affiliation

¹ Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0212F, USA. lwest@rx.uga.edu

PMID: 16872132
DOI: 10.1021/np050459c

Abstract

Three new hexaprenoid hydroquinones, adociaquinol (1), adociasulfate 11 (2), and adociasulfate 12 (3), together with the known adociasulfates 2, 4, and 6, were isolated from the marine sponge Haliclona (aka Adocia) sp. The structures of these compounds were elucidated by interpretation of spectroscopic data.

MeSH terms

Animals
Drug Screening Assays, Antitumor
Humans
Hydroquinones* / chemistry
Hydroquinones* / isolation & purification
Hydroquinones* / pharmacology
Molecular Structure
Palau
Porifera / chemistry*
Sulfuric Acid Esters* / chemistry
Sulfuric Acid Esters* / isolation & purification
Sulfuric Acid Esters* / pharmacology
Triterpenes* / chemistry
Triterpenes* / classification
Triterpenes* / isolation & purification
Triterpenes* / pharmacology
Tumor Cells, Cultured

Substances

Hydroquinones
Sulfuric Acid Esters
Triterpenes
adociaquinol
adociasulfate 11
adociasulfate 12