This is the first report describing lymphedema of the lower limb after surgery for ovarian cancer complicated by severe cellulitis with systemic inflammatory response syndrome (SIRS). Debridement of the lesion and a split-thickness graft were required for a complete cure. Although lymphedema as a complication after surgery for gynecologic malignancies is prone to be considered less serious on the medical side, it is considered necessary to treat lymphedema of the lower limbs while it is still in a mild state since severe cellulitis may accompany lymphedema, as in the present case.