Abstract
The Dictyostelium rbrA gene encodes a putative Ariadne ubiquitin ligase. rbrA(-) cells form defective slugs that cannot phototax. Prestalk cell numbers are reduced in rbrA(-) slugs, and these prestalk cells do not localize to the tip of slugs. Chimeric slugs containing wild-type cells could phototax and form fruiting bodies.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Dictyostelium / cytology
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Dictyostelium / enzymology*
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Dictyostelium / growth & development*
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Gene Expression
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Genes, Protozoan / genetics
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Molecular Sequence Data
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Mutation / genetics
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Phenotype
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Recombinant Fusion Proteins / metabolism
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Spores / metabolism
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Ubiquitin-Protein Ligases / chemistry
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Ubiquitin-Protein Ligases / metabolism*
Substances
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Recombinant Fusion Proteins
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Ubiquitin-Protein Ligases