Determination of degree of substitution of formyl groups in polyaldehyde dextran by the hydroxylamine hydrochloride method

Pharm Res. 1991 Mar;8(3):400-2. doi: 10.1023/a:1015866104055.

Abstract

Colorimetric or potentiometric titration of the aldehyde residues in polyaldehyde dextran by the hydroxylamine hydrochloride/sodium hydroxide method has been found to be a convenient and accurate method to determine formyl content. Nitrogen combustion analyses on the isolated oximes confirmed the titrametric results.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / analysis
  • Colorimetry / methods
  • Dextrans / analysis*
  • Hydroxylamine
  • Hydroxylamines* / analysis
  • Nitrogen / analysis
  • Potentiometry / methods

Substances

  • Aldehydes
  • Dextrans
  • Hydroxylamines
  • Hydroxylamine
  • dextran dialdehyde
  • Nitrogen