Antibiotic resistance of Campylobacter jejuni and Campylobacter coli clinical isolates from Poland

Antimicrob Agents Chemother. 2007 Mar;51(3):1123-5. doi: 10.1128/AAC.01187-06. Epub 2007 Jan 8.

Abstract

We tested 102 Campylobacter jejuni and 6 Campylobacter coli clinical isolates from Poland. All were susceptible to erythromycin. Among the tested C. jejuni isolates 55.9% and 13.7% were resistant to ciprofloxacin and tetracycline, respectively. Replacement of Thr86 with Ile in GyrA and a plasmid-borne tet(O) gene were the main resistance mechanisms for fluoroquinolones and tetracycline, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Campylobacter Infections / microbiology
  • Campylobacter coli / drug effects*
  • Campylobacter jejuni / drug effects*
  • DNA Gyrase / genetics
  • DNA, Bacterial / genetics
  • Drug Resistance, Bacterial*
  • Electrophoresis, Polyacrylamide Gel
  • Feces / microbiology
  • Humans
  • Microbial Sensitivity Tests
  • Plasmids / genetics
  • Poland
  • Polymorphism, Restriction Fragment Length
  • Tetracycline Resistance

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • DNA Gyrase