Hyponatraemia and hypokalaemia during intravenous fluid administration

Arch Dis Child. 2008 Apr;93(4):285-7. doi: 10.1136/adc.2006.093823. Epub 2007 Jan 9.

Abstract

Background: Hospital-acquired hyponatraemia is associated with excessive volumes of hypotonic intravenous fluids and can cause death or permanent neurological deficit.

Methods: A cross-sectional survey was carried out in 17 hospitals on all children receiving intravenous fluids during 1 day of a specified week in December 2004.

Results: 77 of 99 children receiving intravenous fluids received hypotonic solutions and 38% received >105% of fluid requirements. 21 of 86 children were hyponatraemic, but the electrolytes of only 79% had been checked in the preceding 48 h.

Conclusions: Intravenous fluids should be used with caution as regards the tonicity and volume administered, and with appropriate monitoring of serum electrolytes.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • England / epidemiology
  • Fluid Therapy / adverse effects*
  • Fluid Therapy / methods
  • Humans
  • Hypokalemia / epidemiology
  • Hypokalemia / etiology*
  • Hyponatremia / epidemiology
  • Hyponatremia / etiology*
  • Hypotonic Solutions / adverse effects*
  • Infant
  • Infant, Newborn
  • Infusions, Intravenous
  • Time Factors

Substances

  • Hypotonic Solutions