Evaluation of a novel enzyme-linked immunosorbent assay to detect immunoglobulin G antibody to enolase for serodiagnosis of invasive candidiasis

Clin Vaccine Immunol. 2007 Mar;14(3):318-9. doi: 10.1128/CVI.00396-06. Epub 2007 Jan 17.

Abstract

The performance of a new test to detect antibodies to Candida albicans recombinant enolase was investigated in 47 immunocompromised and 51 immunocompetent patients. The sensitivity, specificity, and positive and negative predictive values of the test for the diagnosis of invasive candidiasis were 81.0, 83.9, 79.1, and 85.5%, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Fungal / blood*
  • Candida albicans / immunology*
  • Candidiasis / diagnosis*
  • Enzyme-Linked Immunosorbent Assay / methods*
  • Humans
  • Immunoglobulin G / blood*
  • Phosphopyruvate Hydratase / immunology*
  • Retrospective Studies
  • Sensitivity and Specificity
  • Serologic Tests

Substances

  • Antibodies, Fungal
  • Immunoglobulin G
  • Phosphopyruvate Hydratase