The leptin connection: regulatory T cells and autoimmunity

Kim J Hasenkrug

doi:10.1016/j.immuni.2007.02.002

The leptin connection: regulatory T cells and autoimmunity

Immunity. 2007 Feb;26(2):143-5. doi: 10.1016/j.immuni.2007.02.002.

Author

Kim J Hasenkrug¹

Affiliation

¹ Laboratory of Persistent Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA. khasenkrug@nih.gov

PMID: 17307702
DOI: 10.1016/j.immuni.2007.02.002

Abstract

Leptin is a cytokine-like hormone with proinflammatory properties linked to autoimmune diseases. In this issue of Immunity, De Rosa et al. (2007) elucidate an important new role for leptin in the anergy and hyporesponsiveness of regulatory T cells.

Publication types

Comment
Review

MeSH terms

Animals
Autoimmunity*
Clonal Anergy
Humans
Leptin / immunology*
T-Lymphocytes, Regulatory / immunology*

Substances

Leptin