A case of naturally acquired inhalation anthrax: clinical care and analyses of anti-protective antigen immunoglobulin G and lethal factor

Clin Infect Dis. 2007 Apr 1;44(7):968-71. doi: 10.1086/512372. Epub 2007 Feb 26.

Abstract

This report describes the first case of naturally acquired inhalation anthrax in the United States since 1976. The patient's clinical course included adjunctive treatment with human anthrax immunoglobulin. Clinical correlation of serologic assays for the lethal factor component of lethal toxin and anti-protective antigen immunoglobulin G are also presented.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anthrax / diagnosis*
  • Anthrax / therapy*
  • Anthrax Vaccines / administration & dosage*
  • Anthrax Vaccines / immunology
  • Antigens, Bacterial / immunology*
  • Bacillus anthracis / isolation & purification
  • Blood Chemical Analysis
  • Environmental Exposure / adverse effects
  • Enzyme-Linked Immunosorbent Assay
  • Exotoxins / blood
  • Follow-Up Studies
  • Humans
  • Immunoglobulin G / immunology*
  • Immunoglobulin G / metabolism
  • Inhalation
  • Male
  • Risk Assessment
  • Severity of Illness Index
  • Travel
  • United States

Substances

  • Anthrax Vaccines
  • Antigens, Bacterial
  • Exotoxins
  • Immunoglobulin G