Iron dependent degradation of an isothiazolone biocide (5-chloro-2-methyl-4-isothiazolin-3-one)

Biofouling. 2007;23(1-2):73-7. doi: 10.1080/08927010601149729.

Abstract

An isothiazolone biocide, 5-chloro-2-methyl-4-isothiazolin-3-one (CMI), was degraded in the presence of iron. According to the Fe-dependent degradation of CMI, stoichiometric production of chloride was observed. Copper and stainless steel did not enhance the physico-chemical degradation of CMI, whilst phosphate inhibited the Fe-dependent degradation. Neither aerobic nor anaerobic conditions influenced the Fe-dependent CMI degradation. Furthermore, FeO(OH)-powder and Fe(3)O(4)-powder did not lead to the physico-chemical degradation of CMI. Rapid disappearance of CMI was observed in an operating cooling water plant. CMI added to the cooling tower declined from 1.4 mg l(-1) to < 0.1 mg l(-1) in 2 d. This finding is important in optimising the use of CMI and combating resistance if encountered.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aerobiosis
  • Anaerobiosis
  • Biodegradation, Environmental
  • Biofilms / drug effects
  • Biofilms / growth & development
  • Chemical Phenomena
  • Chemistry, Physical
  • Disinfectants* / metabolism
  • Disinfectants* / pharmacology
  • Iron
  • Thiazoles* / metabolism
  • Thiazoles* / pharmacology
  • Water Microbiology

Substances

  • Disinfectants
  • Thiazoles
  • 5-chloro-2-methyl-4-isothiazolin-3-one
  • Iron