Abstract
With the use of the micronuclear test method it has been shown that mice preirradiated with gamma rays at a low dose rate exhibit a decreased frequency of chromosome aberrations induced in bone marrow cells by subsequent acute exposure to gamma radiation as compared to mice not subjected to preliminary irradiation. Such animals have a higher radioresistance with respect to the survival rate. The results obtained suggest the possibility of induction by ionizing radiation, at a low dose rate, of adaptive repair response at the organism level.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Adaptation, Physiological / radiation effects
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Animals
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Bone Marrow / radiation effects*
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Bone Marrow / ultrastructure
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Chromosome Aberrations
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Dose-Response Relationship, Radiation
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Erythrocytes / radiation effects
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Erythrocytes / ultrastructure
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Gamma Rays
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Male
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Mice
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Mice, Inbred Strains
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Micronuclei, Chromosome-Defective / radiation effects*
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Micronuclei, Chromosome-Defective / ultrastructure
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Micronucleus Tests
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Radiation Injuries, Experimental / mortality
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Radiation Injuries, Experimental / pathology
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Whole-Body Irradiation