Abstract
Both invasion of the host cell by T. cruzi and its establishment into the mammalian host are critical steps. In this review, the adhesion step and the intracellular survival in non-professional phagocytes are particularly focused on, with special emphasis on the role of Gp85/trans-sialidase (Gp85/TS) superfamily. Excellent reviews have been published lately, some covering other aspects of T. cruzi-host interaction and will be cited instead of the original articles due to limited number of listed references.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Cell Adhesion / physiology*
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Cell Survival / physiology*
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Chagas Disease / immunology
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Chagas Disease / microbiology
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Host-Parasite Interactions
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Humans
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Peptide Hydrolases / metabolism
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Protozoan Proteins / metabolism
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Trypanosoma cruzi* / metabolism
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Trypanosoma cruzi* / pathogenicity
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Variant Surface Glycoproteins, Trypanosoma / metabolism
Substances
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Protozoan Proteins
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Variant Surface Glycoproteins, Trypanosoma
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Peptide Hydrolases