Abstract
A child had the characteristic clinical and EEG pattern of migrating partial seizures in infancy with left temporal lobe atrophy, hippocampal sclerosis and cortical-subcortical blurring. Seizures were drug-resistant, with recurring episodes of status epilepticus. The child developed microcephaly with arrest of psychomotor development. Focal brain lesions, in the context of migrating partial seizures, have not been previously reported.[Published with video sequences].
MeSH terms
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Atrophy / pathology
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Brain Diseases / diagnosis*
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Brain Diseases / epidemiology
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Child, Preschool
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Comorbidity
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Electroencephalography / statistics & numerical data
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Epilepsies, Partial / diagnosis*
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Epilepsies, Partial / epidemiology
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Epilepsy, Temporal Lobe / epidemiology
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Epilepsy, Temporal Lobe / pathology
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Female
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Functional Laterality
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Hippocampus / pathology*
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Humans
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Magnetic Resonance Imaging
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Microcephaly / epidemiology*
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Psychomotor Disorders / epidemiology
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Psychomotor Disorders / pathology
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Sclerosis / pathology
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Status Epilepticus / diagnosis
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Status Epilepticus / epidemiology
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Temporal Lobe / pathology*