MareyMap: an R-based tool with graphical interface for estimating recombination rates

Bioinformatics. 2007 Aug 15;23(16):2188-9. doi: 10.1093/bioinformatics/btm315. Epub 2007 Jun 22.

Abstract

Comparing genetic and physical maps (the so-called Marey map approach) is still the most widely used approach to estimate genome-wide recombination rates. Remarkably, there is no available bioinformatics tool specifically devoted to Marey map approach. Here, we developed such a tool called MareyMap based on GNU R and Tcl/Tk. MareyMap offers a user-friendly graphical interface and includes useful features, such as data cleaning process, sophisticated interpolation methods to estimate local rates, possibility of complex queries, various range of import-export files. Moreover, MareyMap comes with ready-to-use maps for human, Drosophila, Caenorhabditis elegans and Arabidopsis. MareyMap has been made so that it can be easily upgraded with new data and interpolation methods.

Availability: http://pbil.univ-lyon1.fr/software/mareymap/.

MeSH terms

  • Chromosome Mapping / methods*
  • Computer Graphics*
  • Computer Simulation
  • Genetic Variation / genetics*
  • Models, Genetic
  • Programming Languages*
  • Recombination, Genetic / genetics*
  • Software*
  • User-Computer Interface*