Gold(I)-catalyzed regioselective cyclizations of silyl ketene amides and carbamates with alkynes

J Org Chem. 2007 Aug 3;72(16):6287-9. doi: 10.1021/jo071014r. Epub 2007 Jul 11.

Abstract

The gold(I)-catalyzed regioselective cyclizations of silyl ketene amides or carbamates with alkynes were utilized to construct cyclopentanes or dehydro-delta-lactams.

MeSH terms

  • Alkynes / chemistry*
  • Carbamates / chemistry*
  • Catalysis
  • Chemistry, Organic / methods*
  • Cyclization
  • Ethylenes / chemistry*
  • Gold / chemistry*
  • Ketones / chemistry*
  • Magnetic Resonance Spectroscopy
  • Models, Chemical
  • Molecular Structure
  • Stereoisomerism
  • Temperature

Substances

  • Alkynes
  • Carbamates
  • Ethylenes
  • Ketones
  • Gold
  • ketene