Modern concept of vascular cognitive impairment

Br Med Bull. 2007:83:291-305. doi: 10.1093/bmb/ldm021. Epub 2007 Aug 4.

Abstract

Background: Vascular cognitive impairment (VCI) has superseded vascular dementia and multi-infarct dementia as the concept to be used in cognitive decline due to cerebrovascular disease.

Method: The literature was reviewed with regard to the concept of VCI and its incidence, pathophysiological substrate, clinical features and management.

Results: A change in the diagnostic paradigm from the current Alzheimer-based definition of vascular dementia to VCI will allow the earlier identification of cases and will identify a different population from that recognized using the current criteria for vascular dementia.

Conclusions: Case identification at the earliest possible stage affords the greatest opportunity for treatment that may slow the rate of progression.

Publication types

  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / complications
  • Cerebrovascular Disorders / complications
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / etiology
  • Dementia, Vascular / diagnosis
  • Dementia, Vascular / epidemiology*
  • Dementia, Vascular / etiology
  • Diagnosis, Differential
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prognosis
  • Risk Factors