Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste

Angew Chem Int Ed Engl. 2007;46(40):7697-9. doi: 10.1002/anie.200701189.
No abstract available

MeSH terms

  • Animals
  • Binding Sites
  • Carbonic Anhydrase Inhibitors / chemistry*
  • Carbonic Anhydrase Inhibitors / pharmacology*
  • Carbonic Anhydrases / chemistry*
  • Carbonic Anhydrases / metabolism*
  • Humans
  • Isoenzymes / antagonists & inhibitors
  • Isoenzymes / metabolism
  • Metals*
  • Mice
  • Models, Molecular
  • Molecular Structure
  • Saccharin / chemistry*
  • Saccharin / pharmacology*
  • Taste*

Substances

  • Carbonic Anhydrase Inhibitors
  • Isoenzymes
  • Metals
  • Carbonic Anhydrases
  • Saccharin