Reduction of aldehydes and ketones by transfer hydrogenation with 1,4-butanediol

Hannah C Maytum; Bahareh Tavassoli; Jonathan M J Williams

doi:10.1021/ol702029n

Reduction of aldehydes and ketones by transfer hydrogenation with 1,4-butanediol

Org Lett. 2007 Oct 11;9(21):4387-9. doi: 10.1021/ol702029n. Epub 2007 Sep 14.

Authors

Hannah C Maytum¹, Bahareh Tavassoli, Jonathan M J Williams

Affiliation

¹ Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.

PMID: 17854202
DOI: 10.1021/ol702029n

Abstract

1,4-Butanediol has been used as the hydrogen donor in transfer hydrogenation reactions. The equilibrium is driven by the formation of gamma-butyrolactone, and the diol is therefore not required in excess.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

4-Butyrolactone / chemistry*
Aldehydes / chemistry*
Butylene Glycols / chemistry*
Combinatorial Chemistry Techniques
Ketones / chemistry*
Molecular Structure
Oxidation-Reduction

Substances

Aldehydes
Butylene Glycols
Ketones
1,4-butanediol
4-Butyrolactone