Abstract
The aim of this study was to estimate: the frequency of aerobic vaginitis, susceptibility of the GBS isolated from vagina of non-pregnant women with and without cervicitis to selected antibiotics and chemotherapeutics and the proinflammatory cytokines production by HeLa, THP-I, U - 937 cells after stimulation by vaginal GBS. Our results indicated low frequency of the aerobic vaginitis -4.5% among non-pregnant young women and ability of the vaginal GBS to release proinflammatory cytokines by human cell lines in vitro.
MeSH terms
-
Adult
-
Anti-Bacterial Agents
-
Bacteria, Aerobic / isolation & purification
-
Bacteria, Aerobic / metabolism
-
Cells, Cultured
-
Coculture Techniques
-
Cytokines / metabolism*
-
Female
-
Gardnerella vaginalis / isolation & purification
-
HeLa Cells / metabolism
-
Humans
-
Interleukin-1beta / analysis
-
Interleukin-6 / analysis
-
Interleukin-8 / analysis
-
Macrophage Activation
-
Male
-
Streptococcal Infections / microbiology*
-
Streptococcus agalactiae / isolation & purification
-
Streptococcus agalactiae / metabolism*
-
Tumor Necrosis Factor-alpha / analysis
-
U937 Cells / metabolism
-
Uterine Cervicitis / immunology*
-
Uterine Cervicitis / microbiology*
-
Vaginosis, Bacterial / microbiology*
Substances
-
Anti-Bacterial Agents
-
Cytokines
-
Interleukin-1beta
-
Interleukin-6
-
Interleukin-8
-
Tumor Necrosis Factor-alpha