Direct extraction of astaxanthin from Haematococcus culture using vegetable oils

Biotechnol Lett. 2008 Mar;30(3):441-4. doi: 10.1007/s10529-007-9578-0. Epub 2007 Oct 31.

Abstract

A green, downstream process using common vegetable oils was used for the direct extraction of astaxanthin from Haematococcus. The process consists of a single integrated unit to extract astaxanthin with subsequent separation of the astaxanthin-containing oil extract. Without a cell harvest process step, the culture broth was directly mixed with the vegetable oils; the astaxanthin inside the cell was extracted into the vegetable oil phase by hydrophobic interactions, with recovery yields of 88% and above. The oil extracts were simply separated from the culture medium containing cell debris by gravity settling only.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chlorophyta / chemistry*
  • Chlorophyta / growth & development
  • Culture Media
  • Plant Oils*
  • Xanthophylls / isolation & purification

Substances

  • Culture Media
  • Plant Oils
  • Xanthophylls
  • astaxanthine