The implausibility of metabolic cycles on the prebiotic Earth

PLoS Biol. 2008 Jan;6(1):e18. doi: 10.1371/journal.pbio.0060018.

Abstract

It has been suggested that complex reaction cycles, analogous to metabolic cycles, operated on the primitive Earth prior to the origin of genetic systems, but severe difficulties arise when these proposals are scrutinized from the standpoint of chemical plausibility.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biological Evolution
  • Carbon Dioxide / metabolism
  • Citric Acid Cycle
  • Earth, Planet*
  • Enzymes / metabolism
  • Evolution, Chemical*
  • Origin of Life
  • Peptides / metabolism

Substances

  • Enzymes
  • Peptides
  • Carbon Dioxide