Discovery of chromone-based inhibitors of the transcription factor STAT5

Chembiochem. 2008 Mar 25;9(5):723-7. doi: 10.1002/cbic.200700701.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Aldehydes / pharmacology
  • Cell Line, Tumor
  • Chromones / chemistry
  • Chromones / pharmacology*
  • DNA / drug effects
  • Drug Screening Assays, Antitumor
  • Humans
  • Hydrazones / chemistry
  • Hydrazones / pharmacology*
  • Ligands
  • Molecular Structure
  • STAT5 Transcription Factor / antagonists & inhibitors*
  • Signal Transduction / drug effects
  • Small Molecule Libraries
  • Structure-Activity Relationship
  • src Homology Domains / drug effects

Substances

  • Aldehydes
  • Chromones
  • Hydrazones
  • Ligands
  • STAT5 Transcription Factor
  • Small Molecule Libraries
  • DNA