FTFD: an informatics pipeline supporting phylogenomic analysis of fungal transcription factors

Bioinformatics. 2008 Apr 1;24(7):1024-5. doi: 10.1093/bioinformatics/btn058. Epub 2008 Feb 26.

Abstract

Summary: Genomes of more than 60 fungal species have been sequenced to date, yet there has been no systematic approach to analyze fungal transcription factors (TFs) kingdom widely. We developed a standardized pipeline for annotating TFs in fungal genomes. Resulting data have been archived in a new database termed the Fungal Transcription Factor Database (FTFD). In FTFD, 31,832 putative fungal TFs, identified from 62 fungal and 3 Oomycete species, were classified into 61 families and phylogenetically analyzed. The FTFD will serve as a community resource supporting comparative analyses of the distribution and domain structure of TFs within and across species.

Availability: All data described in this study can be browsed through the FTFD web site at http://ftfd.snu.ac.kr/.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Mapping / methods*
  • Database Management Systems*
  • Databases, Protein*
  • Evolution, Molecular*
  • Fungal Proteins / genetics*
  • Genomics / methods
  • Multigene Family / genetics*
  • Phylogeny
  • Transcription Factors / genetics*

Substances

  • Fungal Proteins
  • Transcription Factors