Abstract
Purpose:
To report 2 cases of Comamonas acidovorans keratitis in immunocompromised cornea.
Methods:
A complete review of the medical records of the two cases of Comamonas acidovorans keratitis.
Results:
We found some similarities in clinical courses of two cases. Both of them showed development of keratitis during the management with corticosteroids, delayed onset, slow response to antibiotics, and relatively less affected corneal epithelium.
Conclusions:
Comamonas acidovorans is known as a less virulent organism. However it can cause an indolent infection that responds slowly even to adequate antibiotics therapy in immunocompromised corneas.
MeSH terms
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Amikacin / therapeutic use
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Anti-Bacterial Agents / therapeutic use
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Ceftazidime / therapeutic use
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Ciprofloxacin / therapeutic use
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Corneal Ulcer / diagnosis
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Corneal Ulcer / drug therapy
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Corneal Ulcer / microbiology*
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Delftia acidovorans / isolation & purification*
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Drug Therapy, Combination
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Eye Infections, Bacterial / diagnosis
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Eye Infections, Bacterial / drug therapy
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Eye Infections, Bacterial / microbiology*
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Gram-Negative Bacterial Infections / diagnosis
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Gram-Negative Bacterial Infections / drug therapy
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Gram-Negative Bacterial Infections / microbiology*
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Humans
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Immunocompromised Host*
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Male
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Microbial Sensitivity Tests
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Middle Aged
Substances
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Anti-Bacterial Agents
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Ciprofloxacin
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Amikacin
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Ceftazidime