Abstract
Epithelial-mesenchymal transition (EMT) is a developmental process in which epithelial cells acquire the motile, migratory properties of mesenchymal cells. In a recent issue of Cell, Mani et al. (2008) show that induction of EMT stimulates cultured breast cells to adopt characteristics of stem cells.
Publication types
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Introductory Journal Article
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Comment
MeSH terms
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Animals
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Biomarkers, Tumor
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Breast Neoplasms / pathology
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CD24 Antigen / metabolism
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Cell Movement
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Cell Transdifferentiation*
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Cell Transformation, Neoplastic
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Epithelial Cells / cytology*
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Female
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Humans
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Hyaluronan Receptors / metabolism
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Mesenchymal Stem Cells / cytology*
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Mesoderm / cytology
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Mesoderm / physiology
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Neoplasm Invasiveness
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Neoplastic Stem Cells / metabolism
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Neoplastic Stem Cells / pathology*
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Tumor Cells, Cultured
Substances
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Biomarkers, Tumor
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CD24 Antigen
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Hyaluronan Receptors