Mild and highly efficient method for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles

J Org Chem. 2008 Sep 5;73(17):6835-7. doi: 10.1021/jo8010232. Epub 2008 Jul 25.

Abstract

A new, convenient method for the syntheses of 2-substituted benzimidazole and benzothizole is described. Short reaction times, large-scale synthesis, easy and quick isolation of the products, excellent chemoselectivity, and excellent yields are the main advantages of this procedure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzimidazoles / chemical synthesis*
  • Benzothiazoles / chemical synthesis*
  • Combinatorial Chemistry Techniques / methods*
  • Magnetic Resonance Spectroscopy
  • Models, Chemical

Substances

  • Benzimidazoles
  • Benzothiazoles
  • benzimidazole