Histone modifications and chromatin remodeling during bacterial infections

Cell Host Microbe. 2008 Aug 14;4(2):100-9. doi: 10.1016/j.chom.2008.07.009.

Abstract

The link between bacteria and host chromatin remodeling is an emerging topic. The exciting recent discoveries on bacterial impact on host epigenetics, as discussed in this Review, highlight yet another strategy used by bacterial pathogens to interfere with key cellular processes. The study of how pathogens provoke host chromatin changes will also provide new insights into host epigenetic regulation mechanisms.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Bacterial Infections / genetics
  • Bacterial Infections / metabolism*
  • Bacterial Infections / microbiology
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Chromatin / genetics
  • Chromatin / metabolism
  • Chromatin Assembly and Disassembly*
  • Epigenesis, Genetic
  • Histones / genetics
  • Histones / metabolism*
  • Host-Pathogen Interactions*
  • Humans
  • Molecular Sequence Data
  • Nucleosomes / metabolism
  • Protein Processing, Post-Translational

Substances

  • Bacterial Proteins
  • Chromatin
  • Histones
  • Nucleosomes