Plasma homovanillic acid in schizotypal personality disorder

Am J Psychiatry. 1991 Sep;148(9):1246-8. doi: 10.1176/ajp.148.9.1246.

Abstract

Schizotypal patients were found to have a significantly higher mean plasma HVA concentration than normal comparison subjects. Furthermore, plasma HVA concentration positively correlated with "psychotic-like" schizotypal symptoms. These results implicate dopaminergic mechanisms modulating the psychotic-like symptoms of schizotypal personality disorder.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Dopamine / physiology
  • Female
  • Homovanillic Acid / blood*
  • Humans
  • Male
  • Personality Disorders / blood
  • Schizophrenic Psychology
  • Schizotypal Personality Disorder / blood*
  • Schizotypal Personality Disorder / physiopathology
  • Schizotypal Personality Disorder / psychology

Substances

  • Dopamine
  • Homovanillic Acid