The effect of C-reactive protein on functional outcome in ischemic stroke patients

Int J Neurosci. 2009;119(3):336-44. doi: 10.1080/00207450802480176.

Abstract

This study was performed to evaluate the effect of C-reactive protein (CRP) measured within 24 hr after stroke onset on functional outcome in ischemic stroke patients. The medical records of 28 first-ever hemiplegic ischemic stroke patients with the lesions on the middle cerebral arterial territory were reviewed. Subjects were classified into experimental group (serum CRP >or= 0.5 mg/dL) and control group (serum CRP<0.5 mg/dL) based on the level of serum CRP measured within 24 hr after stroke onset. Serum CRP measured within 24 hr after stroke onset was significantly correlated with functional scales in ischemic stroke patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Biomarkers / analysis
  • Biomarkers / blood
  • Brain Ischemia / blood
  • Brain Ischemia / diagnosis*
  • Brain Ischemia / physiopathology
  • C-Reactive Protein / analysis
  • C-Reactive Protein / metabolism*
  • Comorbidity
  • Diabetes Mellitus / epidemiology
  • Disease Progression
  • Dyslipidemias / epidemiology
  • Female
  • Heart Diseases / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care / methods*
  • Predictive Value of Tests
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • Stroke / blood
  • Stroke / diagnosis*
  • Stroke / physiopathology
  • Time Factors

Substances

  • Biomarkers
  • C-Reactive Protein