Abstract
Open sesame: Aptamer-substrate complexes activate the coherent operation of two tweezers that act as a "SET-RESET" logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q = quencher, F = fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine Deaminase / metabolism
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Adenosine Monophosphate / chemistry
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Adenosine Monophosphate / metabolism
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Aptamers, Nucleotide / chemistry
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Aptamers, Nucleotide / metabolism
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DNA / chemistry*
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DNA / metabolism
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Logic
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Nucleic Acid Conformation*
Substances
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Aptamers, Nucleotide
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Adenosine Monophosphate
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DNA
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Adenosine Deaminase