Inhibition of PCSK9: a powerful weapon for achieving ideal LDL cholesterol levels

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9546-7. doi: 10.1073/pnas.0904560106. Epub 2009 Jun 8.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Anticholesteremic Agents / pharmacology
  • Anticholesteremic Agents / therapeutic use*
  • Cholesterol, LDL / blood*
  • Drug Design
  • Humans
  • Mice
  • Proprotein Convertase 9
  • Proprotein Convertases
  • Receptors, LDL / metabolism
  • Serine Endopeptidases / drug effects*
  • Serine Endopeptidases / metabolism
  • Serine Proteinase Inhibitors / pharmacology
  • Serine Proteinase Inhibitors / therapeutic use*

Substances

  • Anticholesteremic Agents
  • Cholesterol, LDL
  • Receptors, LDL
  • Serine Proteinase Inhibitors
  • PCSK9 protein, human
  • Proprotein Convertase 9
  • Proprotein Convertases
  • Serine Endopeptidases