Abstract
Analysis of Lyme borreliosis (LB) spirochetes, using a novel multilocus sequence analysis scheme, revealed that OspA serotype 4 strains (a rodent-associated ecotype) of Borrelia garinii were sufficiently genetically distinct from bird-associated B. garinii strains to deserve species status. We suggest that OspA serotype 4 strains be raised to species status and named Borrelia bavariensis sp. nov. The rooted phylogenetic trees provide novel insights into the evolutionary history of LB spirochetes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antigens, Bacterial / genetics
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Antigens, Surface / genetics
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Bacterial Outer Membrane Proteins / genetics
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Bacterial Proteins / genetics*
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Bacterial Typing Techniques
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Bacterial Vaccines / genetics
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Birds / microbiology
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Borrelia / classification*
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Borrelia / genetics
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Borrelia burgdorferi Group / classification
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Borrelia burgdorferi Group / genetics
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DNA, Ribosomal Spacer / genetics
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Humans
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Ixodes / microbiology
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Lipoproteins / genetics
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Lyme Disease / microbiology
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Molecular Sequence Data
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Phylogeny
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Rodentia / microbiology
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Sequence Analysis, DNA*
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Serotyping
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Species Specificity
Substances
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Antigens, Bacterial
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Antigens, Surface
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Bacterial Outer Membrane Proteins
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Bacterial Proteins
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Bacterial Vaccines
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DNA, Ribosomal Spacer
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Lipoproteins
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OspA protein
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OspC protein