Mycoplasma pneumoniae associated with severe autoimmune hemolytic anemia: case report and literature review

Braz J Infect Dis. 2009 Feb;13(1):77-9. doi: 10.1590/s1413-86702009000100018.

Abstract

We report a case of severe hemolytic anemia following Mycoplasma pneumoniae infection in a 29-year-old male patient who was treated with azithromycin. Direct Coombs' test was strongly positive and the cold agglutinin titer was high, with anti-I specificity. Antimycoplasma antibody titer by complement fixation was high 1:10,240. The patient was discharged after 12 days of hospitalization in good health. He remains clinically well with no recurrence of jaundice.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anemia, Hemolytic, Autoimmune / diagnosis
  • Anemia, Hemolytic, Autoimmune / drug therapy
  • Anemia, Hemolytic, Autoimmune / etiology*
  • Anti-Bacterial Agents / therapeutic use
  • Azithromycin / therapeutic use
  • Humans
  • Male
  • Mycoplasma pneumoniae / isolation & purification*
  • Pneumonia, Mycoplasma / complications*
  • Pneumonia, Mycoplasma / diagnosis
  • Pneumonia, Mycoplasma / drug therapy
  • Severity of Illness Index

Substances

  • Anti-Bacterial Agents
  • Azithromycin