Abstract
The genetically heterogeneous taxon Candida parapsilosis was recently reclassified into three species: Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis. The prevalences of these species among 141 bloodstream isolates tested in Brazil were 88% for C. parapsilosis, 9% for C. orthopsilosis, and 3% for C. metapsilosis. Except for three C. orthopsilosis isolates that were considered resistant to 5-flucytosine, all isolates representing the different species of this complex were susceptible to polyenes, triazoles and caspofungin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents / pharmacology*
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Antifungal Agents / therapeutic use
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Brazil / epidemiology
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Candida / classification
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Candida / drug effects*
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Candida / isolation & purification
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Candidiasis / epidemiology*
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Candidiasis / microbiology
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Caspofungin
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DNA, Fungal / analysis
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Drug Resistance, Fungal
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Echinocandins / pharmacology
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Echinocandins / therapeutic use
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Flucytosine / pharmacology
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Flucytosine / therapeutic use
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Fungemia / epidemiology*
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Fungemia / microbiology
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Humans
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Lipopeptides
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Microbial Sensitivity Tests
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Mycological Typing Techniques
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Polyenes / pharmacology
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Polyenes / therapeutic use
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Population Surveillance
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Prevalence
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Triazoles / pharmacology
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Triazoles / therapeutic use
Substances
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Antifungal Agents
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DNA, Fungal
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Echinocandins
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Lipopeptides
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Polyenes
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Triazoles
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Flucytosine
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Caspofungin