This study evaluated the microhardness and elemental composition of various ceramics immersed in acidic agents. One hundred and five discs of fluorapatite-leucite (IPS d.SIGN) and fluorapatite ceramics (IPS e.max Ceram) were randomly divided into 7 groups of 15 each. Five groups were alternately immersed in acidic agents (citrate buffer solution, pineapple juice, green mango juice, cola soft drink and 4% acetic acid) for 30 min and deionized water for 5 min in 7 cycles at 37 degrees C. Two groups were continuously immersed in 4% acetic acid at 80 degrees C for 16 h and deionized water at 37 degrees C for 245 min. Vicker's microhardness and elemental composition were recorded before and after immersion. Data were analyzed using two-way repeated ANOVA and t-test at a significance level 0.05. For IPS d.SIGN, there was statistically significant difference in microhardness values between before and after immersion in the green mango, cola soft drink and 4% acetic acid for 16 h (P < 0.05). However, for IPS e.max Ceram, there was no significant difference between before and after immersion in any of the groups (P > 0.05). EDX results of both ceramics found that the elemental percentage of Na, K, Zr, Al and Si decreased after being immersed in acidic agents.