Recent advancements in control interface technology have made the use of end devices such as power wheelchairs easier for individuals with disabilities, especially persons with movement disorders. In this article, we discuss the current state of control interface technology and the devices available clinically for power wheelchair control. We also discuss our research on novel hardware and software approaches that are revolutionizing joystick interface technology and allowing more customizability for individual users with special needs and abilities. Finally, we discuss the future of control interfaces and what research gaps remain.