Abstract
Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Antibodies, Immobilized / immunology*
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Antibodies, Monoclonal / immunology
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Cell Line, Tumor
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Humans
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Immunoassay / instrumentation
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Immunoassay / methods*
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Male
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Microfluidic Analytical Techniques / instrumentation
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Microfluidic Analytical Techniques / methods*
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Microscopy, Fluorescence
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Neoplastic Cells, Circulating* / immunology
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Neoplastic Cells, Circulating* / pathology
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Prostate-Specific Antigen / immunology*
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Prostatic Neoplasms / blood*
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Prostatic Neoplasms / pathology
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Reproducibility of Results
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Sensitivity and Specificity
Substances
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Antibodies, Immobilized
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Antibodies, Monoclonal
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Prostate-Specific Antigen