Longitudinal modelling of body mass index from birth to 14 years

Obes Facts. 2009;2(5):302-10. doi: 10.1159/000235561. Epub 2009 Sep 10.

Abstract

Background: To examine the tracking of BMI from birth to age 14 years.

Participants and methods: Linear mixed model (LMM) analysis was used to model the trajectories of BMI (n = 1,403). Adiposity rebound was investigated for a subset of individuals (n = 173).

Results: Adolescents who were overweight or obese at 14 years followed a different BMI trajectory from birth compared to those of normal weight. There was a difference between weight status groups for the timing of adiposity rebound (p < 0.001) and BMI at nadir (p < 0.001). The LMM depicted a significant difference in rate of change of BMI over time for males and females (p < 0.001), with female BMI increasing at a faster rate, and for weight status groups (p < 0.005), with the obese cohort having the faster increase in BMI over time. BMI at birth was significantly lower for the normal weight cohort compared to the overweight (p = 0.029) and obese (p = 0.019) cohorts.

Conclusion: This study introduces a powerful analytic tool, LMM, to model BMI and shows that weight status at 14 years is the result of a distinct path in earlier years. Compared to their normal weight peers, overweight and obese adolescents experience an earlier adiposity rebound, with a higher BMI at rebound.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Distribution
  • Body Height
  • Body Mass Index*
  • Body Weight
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Infant
  • Infant, Newborn
  • Linear Models
  • Longitudinal Studies
  • Male
  • Models, Statistical*
  • Obesity / epidemiology*