Two new iridoid glucosides from Hedyotis diffusa

Fitoterapia. 2010 Sep;81(6):515-7. doi: 10.1016/j.fitote.2010.01.010. Epub 2010 Jan 18.

Abstract

Two new iridoid glucosides, named diffusosides A and B, were isolated from the aerial part of Hedyotis diffusa Willd. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis and HRESIMS. These two compounds showed no cytotoxic activity against SMMC-7721, SW480, SW620, Bel7402, and HepG2 cells.

MeSH terms

  • Antineoplastic Agents, Phytogenic / analysis*
  • Drug Screening Assays, Antitumor
  • Drugs, Chinese Herbal / chemistry
  • Glucosides / chemistry
  • Glucosides / isolation & purification
  • Hedyotis / chemistry*
  • Hep G2 Cells
  • Humans
  • Iridoids / chemistry
  • Iridoids / isolation & purification*
  • Molecular Structure
  • Plants, Medicinal / chemistry

Substances

  • Antineoplastic Agents, Phytogenic
  • Drugs, Chinese Herbal
  • Glucosides
  • Iridoids
  • diffusoside A
  • diffusoside B