Desymmetrizations forming tetrasubstituted olefins using enantioselective olefin metathesis

Brice Stenne; Justin Timperio; Jolaine Savoie; Travis Dudding; Shawn K Collins

doi:10.1021/ol100511d

Desymmetrizations forming tetrasubstituted olefins using enantioselective olefin metathesis

Org Lett. 2010 May 7;12(9):2032-5. doi: 10.1021/ol100511d.

Authors

Brice Stenne¹, Justin Timperio, Jolaine Savoie, Travis Dudding, Shawn K Collins

Affiliation

¹ Department of Chemistry, Université de Montréal, C.P. 6128 Station Downtown, Montréal, Québec, Canada H3C 3J7.

PMID: 20337494
DOI: 10.1021/ol100511d

Abstract

Highly reactive chiral Ru-based catalysts possessing C(1)-symmetric N-heterocyclic carbene ligands adorned with one N-alkyl group and one N-aryl group were evaluated in asymmetric desymmetrizations to form cyclic products possessing a tetrasubstituted olefin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkenes / chemistry*
Catalysis
Cyclization
Stereoisomerism

Substances

Alkenes