Overgeneral autobiographical memory as a predictor of the course of depression: a meta-analysis

Behav Res Ther. 2010 Jul;48(7):614-25. doi: 10.1016/j.brat.2010.03.013. Epub 2010 Mar 20.

Abstract

Overgeneral autobiographical memory (OGM) is a robust phenomenon in depression, but the extent to which OGM predicts the course of depression is not well-established. This meta-analysis synthesized data from 15 studies to examine the degree to which OGM 1) correlates with depressive symptoms at follow-up, and 2) predicts depressive symptoms at follow-up over and above initial depressive symptoms. Although the effects are small, specific and categoric/overgeneral memories generated during the Autobiographical Memory Test significantly predicted the course of depression. Fewer specific memories and more categoric/overgeneral memories were associated with higher follow-up depressive symptoms, and predicted higher follow-up symptoms over and above initial symptoms. Potential moderators were also examined. The age and clinical depression status of participants, as well as the length of follow-up between the two depressive symptom assessments, significantly moderated the predictive relationship between OGM and the course of depression. The predictive relationship between specific memories and follow-up depressive symptoms became greater with increasing age and a shorter length of follow-up, and the predictive relationship was stronger for participants with clinical depression diagnoses than for nonclinical participants. These findings highlight OGM as a predictor of the course of depression, and future studies should investigate the mechanisms underlying this relationship.

Publication types

  • Meta-Analysis
  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Age Factors
  • Depressive Disorder / complications*
  • Depressive Disorder / diagnosis*
  • Disease Progression
  • Follow-Up Studies
  • Humans
  • Memory
  • Memory Disorders / complications*
  • Prognosis
  • Psychiatric Status Rating Scales
  • Psychological Tests
  • Time Factors