Brain metastasis from uterine cervical cancer

J Obstet Gynaecol Res. 2010 Jun;36(3):701-4. doi: 10.1111/j.1447-0756.2010.01219.x.

Abstract

Uterine cervical cancer usually spreads by local extension and through the rich lymphatic network to the retroperitoneal lymph nodes. However, brain metastasis from primary cervical cancer is extremely rare. They are usually seen late in the clinical course and have poor prognosis. We present a 48-year-old woman with squamous cell carcinoma of the cervix who developed multiple brain metastases after 30-month treatment of the primary disease. The patient received whole brain radiation therapy and steroids, and she is alive without any neurologic symptoms and signs at the 6-month follow-up after treatment of the recurrence.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / secondary*
  • Carcinoma, Squamous Cell / radiotherapy
  • Carcinoma, Squamous Cell / secondary*
  • Female
  • Humans
  • Lymphatic Metastasis / pathology
  • Lymphatic Metastasis / radiotherapy
  • Middle Aged
  • Treatment Outcome
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / radiotherapy