Increasing incidence of mucormycosis in University Hospital, Belgium

Emerg Infect Dis. 2010 Sep;16(9):1456-8. doi: 10.3201/eid1609.100276.

Abstract

To determine why incidence of mucormycosis infections was increasing in a large university hospital in Belgium, we examined case data from 2000-2009. We found the increase was not related to voriconazole use but most probably to an increase in high-risk patients, particularly those with underlying hematologic malignancies.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antifungal Agents / adverse effects
  • Belgium / epidemiology
  • Child
  • Female
  • Hematologic Neoplasms / complications
  • Hospitals, University
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Mucormycosis / epidemiology*
  • Mucormycosis / etiology
  • Pyrimidines / adverse effects
  • Risk Factors
  • Triazoles / adverse effects
  • Voriconazole
  • Young Adult

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole