Structural elucidations and spectral assigments of two novel triterpene glycosides from Cephalaria paphlagonica

Nat Prod Res. 2010 Sep;24(14):1337-46. doi: 10.1080/14786410903381335.

Abstract

Two novel triterpene glycosides, paphlagonoside A (1) and B (2), were characterised as 28-O-[beta-D-glucopyranosyl(1 --> 2)-alpha-L-arabinopyranosyl(1 --> 4)-beta-D-glucopyranosyl]-hederagenin (1) and 28-O-[beta-D-xylopyranosyl(1 --> 4)-alpha-L-rhamnopyranosyl(1 --> 3)-beta-D-xylopyranosyl (1 --> 6)-beta-D-glucopyranosyl(1 --> 2)-beta-D-glucopyranosyl]-hederagenin (2) from Cephalaria paphlagonica (Dipsacaceae). In addition to these, a common natural product (hederagenin) (3) was also isolated. The structures of all compounds were identified by spectroscopic and chemical methods. The antimicrobial and antioxidant activities of the plant extracts were examined by MIC and DPPH activity methods, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Biphenyl Compounds / metabolism
  • Dipsacaceae / chemistry*
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology*
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Picrates / metabolism
  • Plant Components, Aerial / chemistry
  • Spectrometry, Mass, Electrospray Ionization
  • Spectrophotometry, Ultraviolet
  • Spectroscopy, Fourier Transform Infrared
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology
  • Turkey

Substances

  • Anti-Bacterial Agents
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Glycosides
  • Picrates
  • Triterpenes
  • 1,1-diphenyl-2-picrylhydrazyl